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KMID : 0380020190340010010
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Korean Journal of Biotechnology and Bioengineering
2019 Volume.34 No. 1 p.10 ~ p.14
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Oral Administration of Camelina Oil Effects on Body Weight and Serum Lipid of Mice
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Chung Yong-Suk
Choi Jung-Ran
Lee Sang-Hyeob
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Abstract
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The seed of Camelina sativa is emerging as a good source of α-linolenic acid with enhanced vitamin E content. Therefore, we investigated health beneficial effects of camelina oil for utilization of food ingredient. In this study, we administrated orally camelina oil with normal (ND) and high-fat diet (HFD) feeing on mice and analyzed their effects on lower body weight gain, serum lipid profiling including total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HLD), and low-density lipoprotein (LDL). In ND feeding mice, oral administration of camelina oil showed significantly lower body weight gain after two weeks compare to lack of camelina oil supplement, although the effect of body weight gain was not shown in HFD feeding mice. Camelina oil also effects on lipid profiles of mice serum. The levels of TC were significantly decreased by the camelina oil supplementation in ND feeding mice. These results suggested that camelina oil supplementation with moderate-fat consumption might have health benefits in body weight control and blood lipid profiles.
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KEYWORD
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ALA (alpha linolenic acid), camelina oil, lower body weight gain, omega-3 fatty acid, serum lipid profiling
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